Besedovsky Lab - Publications
2024 2023 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 |
2024
Lutz ND, Martínez-Albert E, Friedrich H, Born J, Besedovsky L. Sleep shapes the associative structure underlying pattern completion in multielement event memory. Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2314423121. doi:10.1073/pnas.2314423121. Epub 2024 Feb 20. PMID: 38377208.
2023
Blaskovich B, Bullón-Tarrasó E, Pöhlchen D, Manafis A, Neumayer H, Besedovsky L, Brückl T; BeCOME Working Group; Simor P, Binder FP, Spoormaker VI.
The utility of wearable headband electroencephalography and pulse photoplethysmography to assess cortical and physiological arousal in individuals with stress-related mental disorders. J Sleep Res. 2023 Dec 15:e14123. doi:10.1111/jsr.14123. Epub ahead of print. PMID: 38099396.
Wilantri S, Grasshoff H, Lange T, Gaber T, Besedovsky L, Buttgereit F.
Detecting and exploiting the circadian clock in rheumatoid arthritis. Acta Physiol (Oxf). 2023 Oct;239(2):e14028. doi: 10.1111/apha.14028. Epub 2023 Aug 23. PMID: 37609862.
Haack M, Engert LC, Besedovsky L, Goldstein MR, Devine JK, Dang R, Olia K, Molina V, Bertisch SM, Sethna N, Simpson N. Alterations of pain pathways by experimental sleep disturbances in humans: central pain-inhibitory, cyclooxygenase, and endocannabinoid pathways. Sleep. 2023 Jun 13;46(6):zsad061. doi: 10.1093/sleep/zsad061. PMID: 36881901; PMCID: PMC10262178.
Miao, X., Müller, C., Lutz, N. D., Yang, Q., Waszak, F., Born, J., & Rauss, K. (2023). Sleep consolidates stimulus–response learning. Learning & Memory, 30(9), 175–184. https://doi.org/10.1101/lm.053753.123
2022
Lange T, Luebber F, Grasshoff H, Besedovsky L. The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic. Pubmed
Besedovsky L, Dang R, Engert LC, Goldstein MR, Devine JK, Bertisch SM, Mullington JM, Simpson N, Haack M. Differential effects of an experimental model of prolonged sleep disturbance on inflammation in healthy females and males. PNAS Nexus. 2022 Mar;1(1):pgac004. doi: 10.1093/pnasnexus/pgac004. Epub 2022 Mar 10. Erratum in: PNAS Nexus. 2024 Jan 30;3(1):pgad455. PMID: 36380854; PMCID:
PMC9648610.
Besedovsky L, Cordi M, Wißlicen L, Martínez-Albert E, Born J, Rasch B. Hypnotic enhancement of slow-wave sleep increases sleep-associated hormone secretion and reduces sympathetic predominance in healthy humans. Commun Biol. 2022 Jul 26;5(1):747. doi: 10.1038/s42003-022-03643-y. PMID: 35882899; PMCID:PMC9325885.
Lange T, Luebber F, Grasshoff H, Besedovsky L. The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic. Semin Immunopathol. 2022 Mar;44(2):239-254. doi: 10.1007/s00281-021-00904-6. Epub 2022 Jan 18. PMID: 35041075; PMCID: PMC8901522.
2021
Schöllhorn A, Schuhmacher J, Besedovsky L, Fendel R, Jensen ATR, Stevanović S, Lange T, Rammensee HG, Born J, Gouttefangeas C, Dimitrov S. Integrin Activation Enables Sensitive Detection of Functional CD4+ and CD8+ T Cells: Application to Characterize SARS-CoV-2 Immunity. Pubmed
2020
Besedovsky L, Benischke M, Fischer J, Yazdi AS, Born J. Human sleep consolidates allergic responses conditioned to the environmental context of an allergen exposure. PubMed
2019
Besedovsky L, Lange T, Haack MThe Sleep-Immune Crosstalk in Health and Disease. PubMed
Dimitrov S, Lange T, Gouttefangeas C, Jensen ATR, Szczepanski M, Lehnnolz J, Soekadar S, Rammensee HG, Born J, Besedovsky L.Gαs-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells. PubMed.
2018
Dimitrov S, Gouttefangeas C, Besedovsky L, Jensen ATR, Chandran PA, Rusch E, Businger R, Schindler M, Lange T, Born J, Rammensee HG. Activated integrins identify functional antigen-specific CD8+ T cells within minutes after antigen stimulation. PubMed
Besedovsky L, Schmidt EM, Linz B, Diekelmann S, Lange T, Born J.Signs of enhanced sleep and sleep-associated memory processing following the anti-inflammatory antibiotic minocycline in men. Pubmed
Besedovsky L, Ngo HV, Dimitrov S, Gassenmaier C, Lehmann R, Born J. Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function. Nat Commun. 2017 Dec 7;8(1):1984. doi:10.1038/s41467-017-02170-3. PMID: 29215045; PMCID: PMC5719447.
2017
Besedovsky L, Ngo HV, Dimitrov S, Gassenmaier C, Lehmann R, Born J. Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function. PubMed
Besedovsky L, Schmidt EM, Linz B, Diekelmann S, Lange T, Born J. Signs of enhanced sleep and sleep-associated memory processing following the anti-inflammatory antibiotic minocycline in men. J Psychopharmacol. 2017 Feb;31(2):204-210. doi: 10.1177/0269881116658991. Epub 2016 Jul 19. PMID:27436232.
2016
Besedovsky L, Dimitrov S, Born J, Lange T. Nocturnal sleep uniformly reduces numbers of different T-cell subsets in the blood of healthy men. PubMed
2015
Besedovsky L, Born J. Sleep, Don't Sneeze: Longer Sleep Reduces the Risk of Catching a Cold.PubMed
Rimmele U, Besedovsky L, Lange T, Born J. Emotional memory can be persistently weakened by suppressing cortisol during retrieval.Pubmed
Dimitrov S, Besedovsky L, Born J, Lange T. Differential acute effects of sleep on spontaneous and stimulated production of tumor necrosis factor in men.
Brain Behav Immun. 2015 Jul;47:201-10. doi: 10.1016/j.bbi.2014.11.017. Epub 2014 Dec 10. PMID: 25500219.
2014
Dimitrov S, Besedovsky L, Born J, Lange T. Differential acute effects of sleep on spontaneous and stimulated production of tumor necrosis factor in men.PubMed
Besedovsky L, Linz B, Dimitrov S, Groch S, Born J, Lange T.Cortisol increases CXCR4 expression but does not affect CD62L and CCR7 levels on specific T cell subsets in humans. Pubmed
Feld GB, Besedovsky L, Kaida K, Münte TF, Born J.Dopamine D2-like receptor activation wipes out preferential consolidation of high over low reward memories during human sleep. Pubmed
Besedovsky L, Linz B, Born J, Lange T. Mineralocorticoid receptor signaling reduces numbers of circulating human naïve T cells and increases their CD62L, CCR7, and CXCR4 expressionPubmed
Schmidt EM, Linz B, Diekelmann S, Besedovsky L, Lange T, Born J. Effects of an interleukin-1 receptor antagonist on human sleep, sleep-associated memory consolidation, and blood monocytes. Brain Behav Immun. 2015 Jul;47:178-85. doi:10.1016/j.bbi.2014.11.012. Epub 2014 Dec 20. PMID: 25535859.
2013
Besedovsky L, Born J, Lange T. Endogenous glucocorticoid receptor signaling drives rhythmic changes in human T-cell subset numbers and the expression of the chemokine receptor CXCR4. PubMed
Rimmele U, Besedovsky L, Lange T, Born J. Blocking mineralocorticoid receptors impairs, blocking glucocorticoid receptors enhances memory retrieval in humans. Neuropsychopharmacology. 2013 Apr;38(5):884-94. doi:10.1038/npp.2012.254. Epub 2012 Dec 6. PMID: 23303058; PMCID: PMC3671995.
2012
Besedovsky L, Born J, Lange T. Blockade of mineralocorticoid receptors enhances naïve T-helper cell counts during early sleep in humans. PubMed
Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch. 2012 Jan;463(1):121-37. doi: 10.1007/s00424-011-1044-0. Epub 2011 Nov 10. PMID:22071480; PMCID: PMC3256323.